BioFem PMS (90 vegi-capsules) (Mfr: BioGenesis Nutraceuticals) (Professional quality product)

Product Number: EM-BIO38
MSRP: ~~$34.00~~
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Manufacturer's Product Comments/Description

Bio-Fem PMS

Bio-Fem PMS contains standardized botanical extracts, antioxidants, vitamins, minerals, amino acids and liver glucuronidation detoxification support.
Supplementation supports menstrual comfort, mood, cramps and edema associated with the menstrual cycle

Vitamin C (Ascorbic Acid): is an antioxidant that protects tissues from free radical damage. Ascorbic acid aides in the regeneration of Vitamin Es antioxidant properties. Connective tissue integrity is dependent on adequate Vitamin C. Beneficial prostaglandin synthesis favoring eicosanoids with antithrombotic and vasodilatory actions are positively influenced with Vitamin C.
Vitamin E: is the principal antioxidant of the lipid bilayer of the cell membrane. It protects polyunsaturated fatty acids and lipoproteins (LDL) from oxidation. Vitamin E is important for heart and blood vessel health, immune health and health of nerve cells and the nervous system. Vitamin E has been shown to promote healthy menstrual function.
Vitamin B6: assists in the reduction of fluid retention via regulation of aldosterone, enhances progesterone levels and reduces symptoms of irritability and fatigue.
Calcium D-Glucurate: encourages a healthy estrogen metabolism through beneficial regulation of glucuronidation in the liver. Calcium D-Glucurate helps the body dispose of toxins and harmful estrogen metabolic end products.
Magnesium: may be beneficial in normalizing brain dopamine often depleted in patients with menstrual cycle dysfunction. Magnesium is often deficient is these patients.
Curcuma longa (Turmeric): is beneficial for uterine, breast and liver health. Curcumin has antioxidant, anti-inflammatory properties.
Dioscorea villosa (Wild Yam): is used industrially as the active agent in the halfsynthesis of steroid hormones such as progesterone. It has ant-spasmodic actions. A common use is for uterine cramping.
Cimicifuga racemosa (Black Cohosh): main indications for use are: premenstrual and dysmenorrheic neurovegetative disorders. Symptoms of sleep disturbances, and emotional symptoms have shown positive benefit with the use of Black Cohosh. Luetinizing hormone levels (LH), but not Follicle Stimulation Hormone (FSH), are significantly reduced with Cimicifuga extracts. Cimicifuga extracts have been shown to potentiate the effects of tamoxifen and do not possess stimulatory effects on estrogen receptor positive cells. Black Cohosh may help prevent bone loss. Extracts were shown to stimulate bone formation even in ovariectomized rats.
Vitex agnus-castus (Chaste Tree): benefits many symptoms of the menstrual cycle including cramping, and menstrual flow regulation.
Vibernum opulus (Cramp Bark): has a long history of use as an antispasmodic, reducing uterine cramping.
Caulophyllum thialictriodes (Blue Cohosh): use dates back to the beginning of the 20th century primarily for menstrual ailments and uterine cramps.
Angelica senesis (Dong Quai): does not appear to have estrogenic actions, rather it appears to enhance estrogen regulation. Its traditional use is as a blood tonic, enhancing the circulation, providing energy, vitality and improved resistance to disease.
Zingiber officinale (Ginger): is an inhibitor of prostaglandin synthesis with a long history of use in uterine cramps and pain.
Paeonia lactiflora (Peony): traditional use has been for women�s hormonal health.
Rutin: has beneficial effects on membrane stability, vascular integrity (blood vessel health), reduction of edema and antiinflammatory properties.
Taurine: is important for a healthy heart, cardiovascular and nervous systems. Some with elevated blood pressure may benefit from use of Taurine. Taurine is beneficial for liver/gallbladder health.
Choline: is important for liver and nervous system health. The major neurotransmitter Acetylcholine requires choline for its synthesis.

Not recommended for use during pregnancy or lactation

References:

Bors W, Michel C, Schikora S. Interaction of flavonoids with ascorbate and determination of their univalent redox potentials: a pulse radiolysis study. Free Rad Biol Med. 19:45-52, 1995.
Cooke MS, Evans MD, Podmore ID, et al. Novel repair action of vitamin C upon in vivo oxidative DNA damage. FEBS Lett. 439:363-367, 1998.
Hwang J, Peterson H, Hodis HN, et al. Ascorbic acid enhances 17 beta-estradiol-mediated inhibition of oxidized low density lipoprotein formation. Atherosclerosis. 150:275-284, 2000.
Taddei S, Virdis A, Ghiadoni L, et al. Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension. Circulation. 97:2222-2229, 1998.
Brigelius-Flohe R, Traber MG. Vitamin E: function and metabolism. FASEB J. 13:1145-1155, 1999. London RS, et al. The effect of alpha-tocopherol on premenstrual symptomatology: a double-blind study. J Am Coll Nutr 2(2):115-122, 1983.
Liske E. Therapeutic efficacy and safety of Cimicifuga racemosa for gynecological disorders. Adv Ther 15:45- 53, 1998.
Barbeau A et al. Deficience en magnesium et dopamine cerebrale, in J Durlach, Ed. First Int. Symposium on Magnesium Deficit in Human Pathology. Paris, F. Vittel. 149-52, 1973.
Sherwood RA et al. Magnesium and the premenstrual syndrome. Ann Clin Biochem 23(6):667-70, 1986. Walaszek Z. Potential use of D-Glucaric acid derivatives in cancer prevention. Cancer Lett. 54:1-8, 1990.
Nesselhut T, Borth S, Kuhn W. Influence of Cimicifuga racemosa extracts with estrogen-like activity on the in vitro proliferation of mamma carcinoma cells. Arch Gynecol Obstet 254:817-8, 1993.
Li JX et al. Effects of Cimicifuga rhizoma on serum calcium and phosphate levels in low calcium dietary rats and on bone mineral density in ovariectomized rats. Phytomed 3(4):379-385, 1996. Yaozy C et al. Analysis of the ingredients of Angelical Sinensis. Kexue Tongbao (Foreign Lang. Ed.) 29:560- 62, 1984.
Werbach MR, Murray MT. Botanical Influences on Illness: A Sourcebook of Clinical Research, 2nd Ed. Third Line Press Inc. Tarzana, CA. 2000.
Werbach MR. Nutritional Influences on Illness: A Sourcebook of Clinical Research, 2nd Ed. Third Line Press, Inc. Tarzana, CA. 1993.
Knight DC, Eden JA. A review of the clinical effects of phytoestrogens. Obstet Genecol 87:897-904, 1996.
Tham DM, Gardner CD, Haskell WL. Clinical review 97: Potential health benefits of dietary phytoestrogens: a review of the clinical, epidemiological, and mechanistic evidence. J Endocrinol Metab 83:2223- 22235, 1998.
Howes L. Update: Isoflavone phyto-oestrogens. Med Observer 1-3, 5 March, 1999.
Hayes KC, Sturman JA. Taurine in metabolism. Ann Rev Nutr. 1:401-425, 1981.
Canty DJ, Zeisel SH. Lecithin and choline in human health and disease. Nutr Rev. 52:327-339, 1994.

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

Manufacturer's Product Details/Ingredients

Six vegi-capsules contain:


Vitamin C (Ascorbic Acid)...................250 mg
Vitamin E...................................100 IU
     (d-Alpha Tocopheryl Succinate)
Vitamin B6...................................50 mg
     (Pyridoxal 5� Phosphate, Pyridoxine HCl)
Calcium D-Glucurate.........................200 mg
     (providing 62 mg of Calcium)
Magnesium (Glycinate, Citrate-Malate).......400 mg
Curcuma longa (95% curcuminoids)............250 mg
Dioscorea villosa (Wild Yam)(10:1)..........250 mg
Cimicifuga racemosa (Black Cohosh)..........250 mg
     (2.5% triterpene glycosides)
Vitex agnus-castus (Chaste Tree)(5:1).......250 mg
Vibernum opulus (Cramp Bark) (5:1)..........250 mg
Caulophyllum thialictriodes.................250 mg
     (Blue Cohosh) (5:1) 
Angelica senesis (Dong Quai) (6:1)..........250 mg
Zingiber officinale.........................150 mg
     (Ginger rhizome 5% gingerols) 
Peony root (Paeonia lactiflora) (5:1).......150 mg
Rutin.......................................600 mg
Taurine.....................................300 mg
Choline (Citrate) ..........................300 mg

Also contains: Cellulose

Suggested Use: Take 2 capsules three times per day starting 10 days prior to menstruation and continuing through the third day of menstruation or as directed by your health care professional.

Warning: Not recommended for use during pregnancy or lactation